Menopause Blood Test, from our experts to you.
Dr Sam Rodgers MBBS, MRCGP

Chief Medical Officer

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What is
menopause?

Menopause is a natural stage of life, which is usually diagnosed when you haven’t had a period for over a year. It’s triggered by a drop in your oestrogen and progesterone levels and means you can no longer get pregnant naturally. 

Typically, menopause starts between the ages of 45 and 55, and most women go through a transition phase known as perimenopause before it begins. Some women’s periods stop completely before they’re 45, and this is known as early (or premature) menopause.


What can I learn from
a menopause test?

Our Menopause Blood Test checks whether you’re likely to be going through menopause by measuring your levels of follicle stimulating hormone (FSH), luteinising hormone (LH), and oestradiol. 

This is especially useful for women under 45, or women with atypical symptoms, where there may be uncertainty. 

Our test also includes thyroid hormone levels to help rule out thyroid conditions, which can have similar symptoms to menopause and become more common with increasing age.


When should I take
a menopause test?

If you're aged 45–55, menopause is usually diagnosed based on symptoms alone. However, a blood test is useful to support a diagnosis of menopause when there is uncertainty, or when symptoms have developed earlier than expected. For example, if you're under 45 and suspect you're going through early menopause, this test can help you check if this is likely.  


Limitations
of the test

Hormone levels fluctuate a lot leading up to menopause — this menopause home test could find that your levels are within normal pre-menopausal ranges one month and show menopausal levels the next. For this reason, we recommend repeating the test the following month to build a clearer picture of your menopausal status. Contraceptives containing oestrogen and progesterone, or high-dose progesterone, will affect your natural FSH and LH levels.

What's Included?

Hormones
Thyroid hormones
Select profile for more information

FSH Follicle Stimulating Hormone (FSH) is produced in the pituitary gland and is important for women in the production of eggs by the ovaries and for men for men in the production of sperm. In the first half of the menstrual cycle in women, FSH stimulates the enlargement of follicles within the ovaries. Each of these follicles will help to increase oestradiol levels. One follicle will become dominant and will be released by the ovary (ovulation), after which follicle stimulating hormone levels drop during the second half of the menstrual cycle. In men, FSH acts on the seminiferous tubules of the testicles where they stimulate immature sperm cells to develop into mature sperm.
LH Luteinising Hormone (LH) is produced by the pituitary gland and is important for male and female fertility. In women it governs the menstrual cycle, peaking before ovulation. In men it stimulates the production of testosterone.
Oestradiol Oestradiol is a female steroid hormone, produced in the ovaries of women and to a much lesser extent in the testes of men. It is the strongest of three oestrogens and is responsible for the female reproductive system as well as the growth of breast tissue and bone thickness. In pre-menopausal women, oestradiol levels vary throughout the monthly cycle, peaking at ovulation. In women, oestradiol levels decline with age, culminating with the menopause when the ovaries stop producing eggs. Low oestradiol can cause many symptoms associated with the menopause, including hot flushes, night sweats and mood swings. Low oestradiol can also cause osteoporosis.
TSH Thyroid stimulating hormone (TSH) is produced in the pituitary gland in order to regulate the production of thyroid hormones thyroxine (T4) and triiodothyronine (T3) by the thyroid gland. If thyroid hormones in the blood are low, then more TSH is produced to stimulate the thyroid gland to produce more of them. If thyroid hormone levels are high, then the pituitary produces less TSH to slow the production of thyroid hormones. If TSH is too high or too low, it normally signifies that there is a problem with the thyroid gland which is causing it to under or over produce thyroid hormones. Sometimes a disorder of the pituitary gland can also cause abnormal TSH levels.
Free thyroxine Thyroxine (T4) is one of two hormones produced by the thyroid gland. It works to speed up the rate of your metabolism. Most T4 is bound to carrier proteins in the blood - it is only the free, or unbound, T4 that is active in the body, which is measured in this test. Free T4 is the less active of the two main thyroid hormones. To have an impact on your cells it needs to convert to the more active T3 when your body needs it.

How to prepare
for your test

Special Instructions

Prepare for your Menopause Blood Test by following these instructions. Please take your sample before 10am. Take this test two to five days after the start of your period, ideally on day three. It can be taken any time if you do not have periods. Hormonal contraception can affect this test, taking a break from this and using barrier contraception will give more accurate results. If you use hormone gels, pessaries, patches, or tablets, we strongly recommend selecting a venous sample to minimise contamination sometimes seen with finger-prick tests. Otherwise, administer any hormone supplements using gloves, and make sure your fingers have not been in contact with hormone supplements for at least four weeks before taking the test. Hormones can be absorbed deep within the skin even after minimal contact and remain there for weeks despite vigorous handwashing. Do not take biotin supplements for two days before this test, discuss this with your doctor if it is prescribed.


Frequently asked questions

What are the symptoms of menopause?
Symptoms of menopause include hot flushes, night sweats, difficulty sleeping, reduced sex drive, and mood changes like anxiety and depression.
Can a blood test tell if I’m perimenopausal?
By measuring LH, FSH, and oestradiol, our menopause test can give an indication of perimenopause, but it can’t be diagnosed through a blood test alone. Your doctor will interpret your Menopause Blood Test results alongside your family and medical history, and your symptoms, to give you personalised advice and any next steps.
How long does menopause last?
On average, menopause symptoms can last for around four years from your last period. But the experience is unique for every woman, and it’s reported that one in ten women experience symptoms for up to 12 years.
Why might I have an early menopause?
Early menopause is when a woman’s periods stop before the age of 45, and there is often no clear cause. Sometimes treatment or surgery for a health condition such as breast cancer may lead to early menopause. Genetics and lifestyle factors like smoking can also play a part.
Can I take a menopause test at home?
Yes, you can take your test at home using our easy menopause test kit. This includes everything you need including a pre-paid return envelope for your sample.

Top tips for healthy menopause 

 

During menopause, hormones fluctuate, and you may start to experience symptoms that affect your daily life. To relieve some of these symptoms, there are simple lifestyle changes you can make, such as getting plenty of rest and eating menopause-friendly foods

It’s also important to look after your mental wellbeing. Sharing advice and personal experiences with family, friends, and colleagues going through the same experience can help. And there are many ways to support others going through menopause

 

Menopause vs thyroid — how to spot the difference?

 

There are many similarities between the symptoms of thyroid conditions and menopause. The only way to tell them apart with certainty is with a blood test. This is why our Menopause Blood Test checks both your thyroid and reproductive hormones. Measuring your thyroid hormones can rule out or indicate that a thyroid condition may be causing your symptoms rather than menopause.

 

Menopause vs perimenopause

 

Menopause is when your periods stop due to lower hormone levels, while perimenopause  (which means around menopause) is the transition phase before you reach menopause. Perimenopause can last from a few months to up to ten years, and during this time, reproductive hormones begin to fluctuate and you may experience symptoms like irregular periods. 

 

Testosterone and the menopause

 

Testosterone in women is converted into oestrogen — the primary female sex hormone. And according to the British Menopause Society (BMS), testosterone deficiency can lead to heightened menopausal symptoms. Too little or too much testosterone can affect your overall health. If you’d like to check your testosterone level alongside key female hormones, our Female Hormone Blood Test can help.

 

Where can I get support for menopause?

 

Whether you’re perimenopausal, menopausal, or post-menopausal, it can be a challenging time. But you’re not alone. There are many charities offering information and support, such as Women’s Health Concern, Menopause Matters, Menopause Café, and Queermenopause for people who identify as LGBTQ+.